Highly selective palladium–benzothiazole carbene-catalyzed allylation of active methylene compounds under neutral conditions

نویسندگان

  • Antonio Monopoli
  • Pietro Cotugno
  • Carlo Giorgio Zambonin
  • Francesco Ciminale
  • Angelo Nacci
چکیده

The Pd-benzothiazol-2-ylidene complex I was found to be a chemoselective catalyst for the Tsuji-Trost allylation of active methylene compounds carried out under neutral conditions and using carbonates as allylating agents. The proposed protocol consists in a simplified procedure adopting an in situ prepared catalyst from Pd2dba3 and 3-methylbenzothiazolium salt V as precursors. A comparison of the performance of benzothiazole carbene with phosphanes and an analogous imidazolium carbene ligand is also proposed.

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عنوان ژورنال:

دوره 11  شماره 

صفحات  -

تاریخ انتشار 2015